Chromosomal assignment of the ovine hairless (hr) gene by fluorescence insitu hybridization

Retrospective assessment of radiation dose by Fluorescence In Situ Hybridization and evaluation of stable chromosomal aberrations

Estimation of absorbed dose for radiation workers or person involved in different radiological accident is the aim of biodosimetry. Cytogenetic methods are the most current and applicable biodosimetry tools. In chronic or protracted exposure, fluorescence in situ hybridization (FISH), stable chromosomal aberration is used for estimation of absorbed dose. For precise estimation of absorbed dose,...

Assignment of the ovine uroporphyrinogen decarboxylase (UROD) gene to chromosome 1p34 --> p36 by fluorescence in situ hybridization.

Heme biosynthesis is a complex multistep process, taking place partly in the cytosol and partly in the mitochondria. A dysfunction of one or more enzymes in the biochemical pathway results in the accumulation of intermediates of the porphyrin synthesis and to the onset of porphyrias. Porphyrias are mainly hereditary; however, they can also be induced by exogenous factors. Depending on which enz...

Assignment of the PHACTR1 gene to bovine chromosome 23q24 by fluorescence in situ hybridization and radiation hybrid mapping.

The phosphatase and actin regulator (PHACTR) proteins represent a family of protein phosphatase 1 (PP1) and actin regulatory proteins. PP1 is a multifunctional enzyme with diverse roles in the nervous system, including regulation of synaptic activity and dendritic morphology. In rat the Phactr1 gene was cloned for the first time as the prototypical member of this family (Allen et al., 2004). By...

Assignment of the human protein tyrosine phosphatase epsilon (PTPRE) gene to chromosome 10q26 by fluorescence in situ hybridization.

Assignment of the canine myosin Va gene (MYO5A) to chromosome 30q14 by fluorescence in situ hybridization and radiation hybrid mapping.

Myosin Va belongs to the unconventional myosin family that has been identified in many non-muscle tissues of vertebrates and invertebrates. All known myosins bind actin and produce mechanical force through ATP hydrolysis. Myosin Va is only expressed in melanocytes and in cells of the neuronal system (Mercer et al., 1991). In melanocytes it is part of the melanosome transport complex (Wu et al.,...